At least half of our children are prescribed at least one medicine each year. But there is often little data on the safety, effectiveness and dosage of these treatments because they are verified by adult clinical trials. We are able to compare paediatric treatment options safely and effectively using embedded trials.

While randomised controlled trials are considered one of the best ways to improve treatment of a condition, they are often costly and complex to run.

Embedded trials are integrated into a patient’s electronic medical record and use data routinely collected during patient care to answer important research questions.

EMR embedded trials embed the identification of suitable patients, consent, randomisation, and collection of data into the electronic medical record.

EMR Embedded Trial Feasibility toolkit

1. Embedded Trial Proposal Checklist
2. Spectrum of Embeddedness Guide  
3. Electronic and Physical workflow assessment 
4. Use knowledge to design trial and embed the trial in EMR   
5. Electronic Phenotyping guidance  

Australian Clinical Trials Alliance (ACTA) Clinical Trials and Registries Symposium 2024

Digital feasibility assessment for clinical trials: from clinical assumptions to EMR reality presentation

Digital Health Week 2023

Embedded Randomised Control Trial Implementation in the Australian Paediatric Hospital Setting

MCRI symposium 2023

Australian Trials Methodology Conference (AUSTRIM) 2021

EMR Embedded Randomised Control Trials Design in the Australian Paediatric Hospital Setting